Engineering Warfare: A Close Look at Biological and Chemical Warfare

Engineering Warfare: A Close Look at Biological and Chemical Warfare

The North Atlantic Treaty Organization handbook dealing with biological warfare defense lists 39 agents, including bacteria, viruses, rickettsiae, and toxins, that could be used as biological weapons. Examining the relationship between aerosol infectivity and toxicity versus quantity of agent illustrates the requirements for producing equivalent effects and narrows the spectrum of possible agents that could be used to cause large numbers of causalities. For example, the amount of agent needed to cover a 100-km2 area and cause 50% lethality is 8 metric tons for even a "highly toxic" toxin such as ricin versus only kilogram quantities of anthrax needed to achieve the same coverage. Thus, deploying an agent such as ricin over a wide area, although possible, becomes impractical from a logistics standpoint, even for a well-funded organization.

The potential impact on a city can be estimated by looking at the effectiveness of an aerosol in producing downwind casualties. The World Health Organization in 1970 modeled the results of a hypothetical dissemination of 50 kg of agent along a 2-km line upwind of a large population center. Anthrax and tularemia are predicted to cause the highest number of dead and incapacitated, as well as the greatest downwind spread. A government study estimated that about 200 pounds of anthrax released upwind of Washington, D.C., could kill up to 3 million people.

Some say that the AIDS virus was engineered. There is a close connection between the rise of genetic engineering and mixing of viruses in the early 1970s and the outbreak of HIV in the late 1970s. This connection persists in the form of the many unprecedented "emerging diseases" caused by "new viruses" that continue up to the present time.

Symptoms of avian influenza in humans have ranged from typical human influenza-like symptoms (e.g., fever, cough, sore throat, and muscle aches) to eye infections, pneumonia, severe respiratory diseases (such as acute respiratory distress), and other severe and life-threatening complications. The symptoms of avian influenza may depend on which virus caused the infection. Studies done in laboratories suggest that some of the prescription medicines approved in the United States for human influenza viruses should work in treating avian influenza infection in humans. However, influenza viruses can become resistant to these drugs, so these medications may not always work. Additional studies are needed to demonstrate the effectiveness of these medicines.



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