Friday, June 27, 2008

Cannabis Reduces Non-Hodgkin Lymphoma Tumor Growth

Cannabis Agonist Reduces Non-Hodgkin Lymphoma Tumor Growth, Study Says

June 26, 2008 - Stockholm, Sweden

Stockholm, Sweden: The administration of the cannabinoid agonist R(+)-MA halts the spread and growth of cancerous tumors in animals with non-Hodgkin lymphoma, according to preclinical data published in the current issue of the International Journal of Cancer. Investigators at the Karolinska Institute in Stockholm reported that mice treated with R(+)-MA experienced a 40 percent reduction in tumor weight.

"The anti-proliferative and proapoptotic (stimulated cell death) effects of cannabinoids make the endocannabinoid system a potential new therapeutic target for individualized therapy in lymphomas," authors concluded.

Earlier this year, the journal Cancer Research reported that the administration of cannabinoids halts the spread of a wide range of cancers, including prostate cancer, breast cancer, lung cancer, pancreatic cancer, and brain cancer.

NORML Deputy Director Paul Armentano has a review of pot's anti-cancer properties online at the Huffington Post.

For more information, please contact Paul Armentano, NORML Deputy Director. Full text of the study, "Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: Growth inhibition by receptor activation," appears in the September issue of the International Journal of Cancer.


Cannabis Agonist Reduces Non-Hodgkin Lymphoma Tumor Growth, Study Says - NORML

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Opening View: American International Group May See Significant Subprime-Related Losses

As expected, Anheuser-Busch (BUD: View sentiment for BUDsentiment, chart, options) formally rejected Belgian brewer InBev's $65-per-share bid, calling the offer "financially inadequate." The Budweiser maker revealed that its board unanimously voted to reject the offer, stating that the proposal "significantly undervalues the unique assets and prospects" of the company.

Bank of America (BAC: View sentiment for BACsentiment, chart, options) was making headlines in afternoon trading yesterday, after reporting plans to cut about 7,500 positions after acquiring Countrywide Financial ( CFC: View sentiment for CFCsentiment, chart, options) – slated for close on July 1. The lay-offs are set to begin in the third quarter. The company stated, "Final decisions on all specific associate groups and locations have not been made." The shares of BAC, which closed at $24.81 yesterday, are poised to continue their trek lower in early activity.

Elsewhere, American International Group (AIG: View sentiment for AIGsentiment, chart, options) plans to absorb up to $5 billion on losses of sales of investments from about 12 insurance units affected by the subprime-mortgage crisis, Bloomberg News reported. The insurer had originally forecast $500 million in investment-sales losses. Ahead of the bell, the security is set to open moderately lower than its close of $28.09 yesterday.



Opening View: American International Group May See Significant Subprime-Related Losses



NYSE Arca Morning Pre Market Trading Update

Stocks trading on NYSE Arca at a price more than 15% away from the previous trade day's consolidated close price. (As of 08:30:00 ET)

Stock
Thursday's Close Current Price Pct Chng Current NYSE Arca Vol
ANDE

$32.93

$38.20

16%

1,325

10 Most Active stocks on NYSE Arca as of 08:30:00 ET

Based on Dollar Volume: Based on Share Volume:
Stock
Dollar Volume
SPY
$170,065,722
QQQQ
$50,828,759
IWM
$14,229,133
RIMM
$11,062,270
USO
$9,426,539
SDS
$8,561,602
ERIC
$7,354,578
BP
$6,140,626
AAPL
$6,135,509
GLD
$6,102,660
Stock
Share Volume
SPY
1,329,396
QQQQ
1,116,005
ERIC
724,751
ESLR
522,952
IWM
204,846
NOK
200,386
SDS
127,765
GFI
114,254
RIMM
91,588
BP
90,700


ANDE:

NYSE Arca Morning Update



Pre Market Trading Gaps

Gapping up:

BDAY +52.2%, ANDE +14.8%, FINL +9.2%, HMY +6.8%, GFI +6.0%, PAYX +5.0%, AKS +4.0%, SOL +3.7%, BRL +3.6%, ACN +2.2%, GOLD +2.1%, TOT +2.0%, SAP +1.5%, SII +1.4%...

Gapping down:

HDSN -7.4%, ERIC -5.9%, LMC -5.2%, HRZB -5.1%, CBK -4.8%, PALM -4.4%, MU -1.7%, BCS -1.6%, DB -1.5%, UBS -1.5%.

Pre-Market Trading Most Active Stocks - NASDAQ Premarket


NASDAQ - Pre-Market Ten Most Advanced

Active Share Volume Declined

Symbol

Company Name

Market
Close
Last Sale (Pre-Market) % Change
(Pre-Market)
Share
Volume

(Pre-Market)

Celebrate Express, Inc.
$2.30 $3.76 63.48% 8,050

Finish Line, Inc. (The)
$6.99 $7.40 5.87% 3,000

Royale Energy, Inc.
$12.75 $13.25 3.92% 10,520

Novell, Inc.
$5.92 $6.15 3.89% 15,366

Randgold Resources Limited
$42.79 $43.89 2.57% 8,870

DryShips Inc.
$82.86 $82.95 0.11% 3,300

QUALCOMM Incorporated
$45.11 $45.12 0.02% 4,400

As of 6/27/2008 8:27:28 AM

NASDAQ - Pre-Market Ten Most Declined

Active Share Volume Advanced

Symbol

Company Name

Market
Close
Last Sale (Pre-Market) % Change
(Pre-Market)
Share
Volume

(Pre-Market)

Evergreen Solar, Inc.
$10.83 $9.86 8.96% 821,917

LM Ericsson Telephone Company
$10.86 $10.02 7.73% 960,051

Rex Energy Corporation
$25.60 $24.32 5.00% 7,116

Sohu.com Inc.
$68.04 $65.05 4.39% 4,545

Wynn Resorts, Limited
$83.50 $81.11 2.86% 7,690

Research in Motion Limited
$123.46 $120.64 2.28% 195,223

Broadcom Corporation
$26.86 $26.30 2.08% 12,002

Apple Inc.
$168.26 $165.44 1.68% 84,483

Home Inns & Hotels Management Inc.
$19.44 $19.16 1.42% 27,886

SunPower Corporation
$76.15 $75.15 1.31% 8,500

As of 6/27/2008 8:27:54 AM



Pre-Market Most Active Stocks - NASDAQ Premarket



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